Recent History
March 25, 1873
Diabetes Mellitus and its dietetic treatment
A group of Cantani's patients (14-20) show that Type 2 Diabetes was effectively represented in the entire population, from young adults to the elderly but required them to eat high starch diets with little to no meat in order to be diagnosed. Anyone who did the rigorous all meat diet would improve in health, even people who never ate meat in the past!
OBSERVATION XIV. - Mr. Rodolfo S., priest of Palma, aged 60, lived only on flour and fruit. In December 1870 he experienced the first symptoms of diabetes, thirst, polyuria, and progressive weight loss; he was very tired of the insomnia. The urine, examined on February 7, 1871, contained 38 gr. of sugar per liter: the patient began my cure on February 8, and already, on the 18th, the urine re-examined was free of sugar; on March 8, the patient began to eat nuts, almonds, limes: the urine remained normal; likewise on August 11, after the patient had returned to the moderate use of bread. He continued to do very well in September 1874. I learned about it from Doctor Carbone de Vico di Palma.
OBSERVATION XV. Doctor Francesco B., from Frascineto in Calabria, doctor in Castrovillari, 39 years old, ate mainly mealy; he had survived two attacks of cholera, in 1867, and experienced great sorrows: recognized diabetic six months ago, after an analysis of the urine, to which he decided, because he suffered from thirst, hunger, polyuria, impotence and extraordinary weakness. He came to see me on November 5, 1871; his urine, examined by Professor Primavera, weighed 1029 and contained 80 gr. of sugar per liter: subject to my treatment, absolute meat diet and lactic acid, after eight days the glycosuria had disappeared. He left Naples a few months later: there was still no sugar, although he had resumed the use of eggs, green vegetables, fruit and a little flour. He wrote to me on March 5, 1873: he assures me that he is doing perfectly, “although he eats everything."
OBSERVATION XVI. - Mr. Raffaele C., wigmaker, 26 years old, from Naples. Suffering for two months from great thirst, hunger, polyuria, impotence, weakness and general wasting, with no other appreciable cause than his almost exclusively floury diet, was treated in Paris with sweet and sour drinks which improved gastric catarrh, but the other symptoms worsened. - When I saw him, on November 15, 1871, he had a polyuria of 5 liters per day, the urine had the specific weight of 1043, and contained, according to the analysis of Professor Primavera, 90 grams. of sugar per liter, which made about 450 gr. of sugar lost in twenty hours: he weighed 49kil, 3.
Submitted to the cure on November 16, his urine was examined on November 23: they were deprived of sugar; all symptoms of diabetes were gone; the patient's weight reached 50 kilograms. From that day on, the improvement continued gradually;
on January 20, 1872, the patient weighed 52,511.7,
on January 26 53kil, 1,
on February 4, 54ki1,8,
on March 8, 56kil, 3,
on March 27, 56k1, 6,
on April 8, 57k1, 1,
on April 27 57kil, 7,
April 30 58 kilog.,
May 24 59 kilog.
He had therefore gained, in six months, 10 kilograms. Today he is doing very well, eats everything and is always fat: seen again by me in the spring of 1874, he appears in an extremely flourishing aspect: he had been happily married for several months. Even today (September 1874), he is doing perfectly well.
OBSERVATION XVII. - MNN, from Malta, aged 40. This gentleman, whom I saw for the first time in consultation with Dr Jos. B. Sammut, was inclined by temperament to polysarcy; all his life he had abused flour and bonbons, never eating meat. Diabetic for six months, he had already followed my treatment in Malta. He nevertheless came to Naples, with 30 gr. of sugar per liter, with three liters of urine per day, so 90 gr. of sugar within twenty-four hours. Subject to all the rigor of our treatment, their quantity was 1750 с. C., and the sugar had completely disappeared. Thus re-established, he made a journey throughout Europe, consulting all the doctors of some renown, and again made a cure in the waters of Carlsbad and those of Vichy. He sent me from Carlsbad an analysis of his urine and a few lines from Dr. Seegen, from which it appears that the sugar had not reappeared although he had extended his diet: I saw him again in December, fully recovered. He wrote to me again on March 25, 1873 that he was doing completely well. On March 10, 1874, he wrote to me again to tell me that his strength and nutrition were fine. well, but after some overeating, small amounts of sugar reappeared and persisted in the urine, although he would have resumed a diet consisting of meat, green vegetables and gluten bread; he was asking me for advice on this. I told him to resume the cure in all its rigor, for a fairly long time (at least three months), and above all to give up gluten bread, which always contains too much starch for a diabetic; however, the patient has so far not wanted to give it up.
OBSERVATION XVIII. - Miss Rosina G., from Piedimonte d'Alife, 20 years old, daughter of a phthisic mother: one of her sisters became diabetic before her. She ate almost exclusively starches and sweets. For three years she has suffered from polyuria, hunger, thirst and severe weight loss: for two years she has been recognized as diabetic, thanks to an analysis made by Professor Primavera in 1868; she was subjected to various cures, in particular that of the waters of Casamicciola d'Ischia: all this was of no use. In the spring of 1870, she received the care of Doctors Caso and Paterno who ordered my treatment; she quickly gained in well-being and nutrition; in a fortnight her urine became free of sugar, and although shortly after she was returned to the mixed diet, to the use of bread and fruit, her urine remained free of sugar: I myself have seen the patient in September, in a good state of nutrition, with normal urine, specific weight of 1019, deprived of sugar. Seeing that she was very eager to eat starchy and sweet foods, I allowed her to do so, while warmly recommending never to abuse, as she did in the past, flour and sweets, surrender a second time. It is interesting to note in this case that, before the disappearance of sugar from the urine, the latter contained a very large quantity of crystals of oxalate of lime, which suggested to me the idea that oxalic acid , in certain cases, could, so to speak, substitute for sugar, in the sense that, the combustion of the hydrocarbons being improved in the organism, these begin to burn, but cannot arrive at a perfect oxidation and decomposition into water and carbonic acid, and thus transform into oxalic acid by incomplete combustion. In diabetes, the combustion of sugar is absolutely lacking, it remains in the state of sugar: the conditions of the organism improving, combustion would manage to produce oxalic acid, before get to be complete. Note that the fact of the appearance of a considerable quantity of oxalate of lime, in the urine, after the disappearance of the sugar, was later verified by me several times, and several other times by Professor Primavera. This young girl is doing well so far: on April 18, 1873, I received a letter from her brother, M. Alfonso G., who recommended me another patient of his acquaintance, adding that her sister was in perfect health. well: I saw her again in August 1873, and lately, in September 1874, I learned from her brother that she is in flourishing health.
OBSERVATION XIX. - The priest C., from Caserta, 38 years old, eating mainly starches, diabetic for 4 years, with 100 gr. of sugar per liter, after having consulted various primary doctors of Naples, and being subjected to various cures by arsenic, strychnine, cod-liver oil, iron, hydrotherapy, etc., was put, in January 1871, the exclusive meat diet, thanks to which the sugar disappeared completely after a rigorous treatment of 40 days. I saw the patient again on September 28, 1871 for a chronic catarrh of the stomach, although he was well fed with normal urine, one to one and a half liters a day, without a trace of sugar, although for a long time. he would have returned to mixed food. I had further direct information on this patient on May 30, 1873, and I knew that he was doing completely well; still today he enjoys perfect health, as I learned in June 1874 from one of his friends, officer in the army.
OBSERVATION XX.-M. Michele L., from Acireale, has always abused extraordinarily fruits and sweets: it was subjected by Doctor Vigo, of Acireale, to my curative method, and cured perfectly. In August 1872, he himself came to Naples, and wanted to see me to make sure that his health had returned: he brought me the analysis of his urine, made on August 22 by Professor Primavera, which testified the complete absence of sugar. A letter from Doctor Vigo, dated June 4, 1873, once again assures me of the perfect health of this patient.
April 12, 1873
Diabetes mellitus and its dietetic treatment.
Cantani's observations on patients 41-50 are translated to English. "he secretly ate the sixth part of a biscuit
OBSERVATION XLI. Mr. Félice F., from Cajazzo, 66, owner, almost exclusive amylivore, recognized diabetic for two months, when he presented, in addition to the symptoms of diabetes, signs of mental alienation: he was submitted on April 4 with notable worsening of symptoms for eight months, presented, on April 26, 1872, urine with a specific weight of 1030, and containing 35 gr. of sugar plus half a gram of albumin per liter. The patient undergoing rigorous treatment, his urine was examined again on May 3: it was absolutely free from sugar; the same on May 15 and 30. Since then I have heard of the complete recovery of this patient, although he had long since returned to mixed food. 1872 to the rigorous cure: after four days the sugar had disappeared, and did not reappear, although the patient quickly returned to mixed food. In this case, we never did a quantitative analysis. The patient continued to be free from diabetes until the latest news, which is about four months old.
OBSERVATION XLII. Doctor Francesco A., doctor of the province of Salerno, 53 years old, great lover of flour, was treated by Professor Primavera, who found, in the first analysis, 105 gr. of sugar per liter: after a week of rigorous treatment accomplished according to my prescriptions, the urine contained only 23 gr. of sugar per liter: the patient admitted that he had continued to eat a little bread: having left it completely, the sugar disappeared entirely, and the patient has enjoyed the best health ever since.
OBSERVATION XLIII. - Mr. Nicola C., from Pisticci (Basilicata) 25 years old, almost exclusively amylivore, ill for an indefinite time, but suffering for a year from ardor, thirst, sexual debilitation, gastro catarrh -enteric with coprostasis, presented on July 22, 1873, according to the analysis of Professor Primavera, 135 gr. of sugar per liter of urine, and the specific weight of 1042: subjected at this time to the cure; from July 29 the urine was free of sugar; they were still in November 1873, according to what his doctor from Pisticci told me, who wrote to me to ask me for advice about an ischialgia from which this patient was suffering, his urine still remaining absolutely normal: they were also such in the last analysis, made by Professor Primavera on February 21, 1874, although the subject had for some time returned to mixed feeding, and even to mealy foods. I saw this patient again on June 24, 1874; his urine, again analyzed by the same professor, was absolutely free of sugar, although he ate during that time, flour in moderate quantities.
OBSERVATION XLIV. - Baron Rodolfo A., from Naples, 34, has always made great use of starches; for only two years, he suffers from a great thirst with polyuria, his general condition progressively worsens, as well as weakness and thinness; this is why in October 1872, he had his urine examined; there was evidence of the presence of sugar. What frightened the patient the most, threatening of the lens; the various cures to which he was subjected had only a mediocre success, because he came to see me on March 30, 1873, with 100 gr. of sugar per liter of urine, according to the analysis of Professor Primavera, and the specific weight of 1040. Submitted to my treatment in all its rigor, from April 6 his urine was free of sugar, weighed 1020 and on the 10th April, 1015. Since that time he has been in perfect health. Professor Primavera has it. core examined urine on June 19; they were completely free of sugar, although the patient had, for some time now, neglected the rigorous treatment. He went well, until the last news received.
OBSERVATION XLV. - Mr. Gennaro M., owner in Santa Maria di Capua Vetere, aged 40; he greatly abused flour and fruit, and also sweet dishes; for some time he had felt an ardor of the mouth, with thirst and polyuria, and in June 1873 he presented all the other symptoms of diabetes, sexual weakness, emaciation, frustration. In October, furunculosis was added to it, and this, by its obs- tession, decided the attending physician, Dr. of 110 gr. of sugar per liter, the specific weight of 1037, a polyuria of 5 to 6 liters per day (which makes 5 to 600 gr. of sugar per 24 hours), and the almost disappearance of urates. Submitted to my treatment in all its rigor, the urine no longer contained, after three days, only 50 gr. of sugar, and, after eight days as 25: after eight more days, sixteen from the start of treatment, the sugar had dropped to 4 gr., and in the fourth week to zero, with abundance of uric acid and urates. - I saw this patient again on December 16; I found him in perfect health, however he complained of a more marked muscular weakness even than before, although he had grown a lot in appearance: later he regained all his strength. - Doctor Fossataro also told me that this patient, when he took a lot of baking soda with lactic acid, had limpid urine with a slight sediment of urates after cooling (note that it was winter) , while taking little or no bicarbonates, it frequently emitted free uric sands. February 3, 1874, almonds, dairy, coffee and wine; his urine was always free of sugar: it remained as it was after the patient had resumed the use of bread and pastries in moderate doses. As to the causes, it should be noted that this patient has always abused farinaceous plants a lot: the occasional causes of diabetes, admitted by the patient, would have been repeated exposure to damp cold, and fear: but by examining the things up close, we see that these acted when the diabetes had started a long time ago: the shock of fear only drew more attention to the patient's state of health; At the most, we can admit after this moral emotion, an aggravation of the disease. - I saw the patient again in July 1874, he was perfectly well (and it was after four months of mixed feeding), flourishing in appearance and ruby in color, with absolutely normal urine (according to Professor Primavera's analysis); it is therefore legitimate to consider this gentleman as perfectly cured. I had further news in September 1874: he was doing the best in the world.
OBSERVATION XLVI. Canon Vincenzo C., 68 years old, from San Severino Lucano, a man endowed with a strong constitution, and a great hunter, feeding mainly on starch, suffered from renal colic, due to uric stones, such as attests to the report of his doctor, Doctor Santagata. For some time now he had suffered from great thirst with exaggerated appetite, and urinated much more profusely than usual. The urine examined on July 10, 1873, discovered sugar in a dose of 30 gr. per liter, showed the specific weight of 1025, with about 3 liters of urine per day; then subjected to the rigorous cure, from July 21 the urine was free of sugar; since then he has always been doing well. In January 1874 I had more good news from him, and yet he had returned to mixed feeding.
OBSERVATION XLVII. - M. Filippo F., aged 34, silversmith in Naples, from a very healthy family, and himself of good health and a robust constitution, gradually experienced an increase in the quantity of urine, up to 16 or 20 urinations per day; at the same time, he felt a dry mouth, and a burning stomach. His urine having been examined by Professor Primavera, according to the advice of 100 gr. of sugar per liter: they were abundant up to 6 or 8 liters per day, which made from 6 to 800 gr. of sugar in 24 hours. The patient could absolutely indicate no cause for his illness; he had experienced no sorrow, no trauma, no morbid history: let us note, however, that he ate a lot of starchy foods, and extraordinarily abused sweet jellies. Submitted to my cure, and following it in all its rigor, the urine had, on September 15th, the specific weight of 1021, its quantity was reduced to a liter or a liter and a half, and the sugar had completely disappeared. Another analysis of December 11 gave the same result, but by the fact of Oliguria the specific gravity was 1027. He then began to eat pastures, milk and dairy products, cheese, olives, salads: he drank wine: later he tried a little piece of bread. He continued to be well, having returned to a moderate mixed diet, although he experienced very great sorrow in February 1874, owing to an illness of his father, who died on February 18, and that he was very afraid of "a recurrence" as a result of this great sorrow. At this time his urine was analyzed, for he was deeply struck; however on March 3 they were completely free of sugar, rare in their quantity (800 gr. in 24 hours) and specifically made 1026: they also contained very-numerous crystals of oxalate of lime; thus the oxa-. luria was substituted in this case, as in several others, for the sweet biabetes. This patient still enjoys today hui (September 1874) in the best health.
OBSERVATION XLVIII.-MTR, of Roccasecca, 40 years old, amylivorous by habit, suffered for about two months, according to the report of his doctor, Doctor Giovinazzi, from an intense thirst with polyuria of 7 to 8 liters per 24 hours, poor hunger, great emaciation and weakness in walking. The chemical examination showed the presence of sugar, which was however not measured. Subjected on April 23, 1873 to the rigorous cure, the sugar, after four days, was reduced to traces: on August 29, urine was sent to Professor Primavera, and the latter, not knowing how it was previously recognized the existence of diabetes, believed in an erroneous diagnosis, so absolute was the absence of any trace of sugar. MTR continued to do well until the last news received, although it has returned to a carefully mixed feed.
OBSERVATION XLIX. The dream. M. A Camilleri, 62 years old, from Nadur del Gozo (Malta), lived to live on mealy and bonbons, a case observed in January 1873, by Dr. P. Sammut, of Gozo, and already published by him. In the grip of progressive weight loss and digestive disturbances for a year, when it was first observed, with a urine emission of 6 to 7 liters per 24 hours, and considerable thirst; these symptoms made Doctor P. Sammut suspect diabetes; urine analysis, with a specific gravity of 1048, confirmed this diagnosis. The mala was so weak at this time that he could not extinguish a candle within eight inches. Subject to my treatment, it improved rapidly: in a few days, the specific weight fell to 1032, after another eight days, to 1026. It was discovered that he secretly ate the sixth part of a biscuit, and this was deleted again: after another twelve days, the urine was completely free of sugar, according to Trommer's test, and weighed 1012 Dr P. Sammut notes that this is the first case of diabetes cured in the island of Gozo, where in the past all diabetics would die without remission (as everywhere else), from the sad consequences of this disease.
OBSERVATION L. Doctor Salvatore Grima, 32 years old, from Casal Kala del Gozo (Malta), courageous amylivore, recognized as diabetic on March 29, 1873, by doctor P. Sammut, with 8 liters per day of urine, a specific weight of 1045: he had lost extraordinary weight. Subject to my treatment, his condition improved in a few days; from April 12, 1873, the urine was completely free of sugar, and all diabetic symptoms were gone; since then he has been doing well. This observation has already been published by Dr. P. Sammut.
July 19, 1873
Diabetes Mellitus and its dietetic treatment.
Cantani describes one of his most serious patients and thinks the rigorous meat-only diet cure would need to be done for 6 months to truly allow a mixed diet thereafter. Observations 71, 72, and the last one 73.
OBSERVATION LXXI. - Mr. Cesare de S., 54 years old, owner in Catanzaro. Suffering from ardor in the mouth and from polyuria since 1871, took a treatment which was prescribed to him by Professor Villanova, and which consisted in the menu of Bouchardat, with iron and strychnine, and later of l 'Lactic acid; the morbid symptoms diminished following this long-followed treatment; on July 19, 1873, he still offered 30 gr. of sugar per liter of urine, the polyuria was 4 to 5 liters per day and the specific weight 1036. This patient affirmed to have always singularly abused mealy and fruits, but was not reached by diabetes until after the grief he had suffered. caused the death of his wife. He affirms, moreover, with all possible precision, that he did not begin to feel better, to gain in strength and in plumpness, until after having begun the use of lactic acid: he assures us that , with him, the absolute meat diet rather diminished general strength. After he had been subjected to my rigorous cure (in July 1873), the urine quickly got rid of the sugar, and on April 15, 1874, long after the patient had returned to the use of bread and pasta (albeit with a moderation very different from the abuse of the past), the urine had the specific gravity of 1.023, and the sugar was absolutely lacking in it, as Professor Primavera found; their quantity was perfectly normal. I had further excellent news from this patient later.
OBSERVATION LXXII. - Mr. Guiseppe Ti ..., 46 years old, notary in S. Elia Pianise (province of Molise), client of Doctor Colaviti, consulted me in May 1872; he had recent diabetes, weighing 50 to 60 g. of sugar per liter, and a polyuria of 3 to 4 liters per day. Subjected to my rigorous cure, after four days the urine was free of sugar; he returned, after having strictly followed the meat diet for two months, to a moderately mixed diet, and remained perfectly cured. - In this case, the diabetes had developed without any cause known to the patient, except experienced grief before having diabetes. But he experienced severe colds, and severe grief about two years after being cured of diabetes, and as, as a result, he experienced pain in his lower back and increasing general weakness, with swelling. legs and strong attacks of dyspnea especially during the night, he was afraid of a return of diabetes, and had his urine examined by Professor Primavera on September 18, 1874. The urine was found to be perfectly free from sugar, it weighed 1014, and were loaded with albumin (10 gr. per liter). From this it follows that a man cured of diabetes does not take it again, even after serious grief, provided that he does not abuse hydrocarbons again, even if, by other morbid causes, he has acquired , at that time, another disease. The following case cannot so far be given for a definitive cure; but in any case it deserves to be cited after the cured cases, because a cure (at least transitory) has been obtained in very difficult circumstances, and because, if the patient were prudent and wise, one could even to regard as assured a lasting cure.
OBSERVATION LXXIII. · Mr. Odoardo G., from Bologna, 22 years old, studying veterinary medicine. He says he suffered from polyarthritis for six months, during his teenage years, and after that he felt a stronger heartbeat. He had measles, smallpox, and intermittent fever. He abused Venus, tobacco and wine. He was very fond of starchy foods, and particularly sweets; of these especially he greatly abused. In September 1873, during the course of a slow disease of which he does not know how to specify the point of departure, he noticed that he was urinating enormously, that he experienced an extraordinary thirst and a great appetite, while he was 'significantly weakened and slimmed down. The analysis then showed the presence in the urine of a large amount of sugar. But already, a year and a half before, he was having fun, he himself said more to play than to calm his thirst, to drink 14 or 15 large glasses of gaseous sugar water; So it seems that the thirst was already increased. It should be noted, however, that four months before realizing his current illness, in about May, he fell while climbing a staircase and violently hit his occipital region: to believe that the disease had started slowly much earlier, especially since the patient, in the month of September, when we noticed the presence of sugar in great proportion in the urine, was already notably weakened and emaciated. On October 3, 1873, he entered one of the most important clinics in Italy. Put on the rigorous diet of the meat diet, the sugar completely disappeared after six days; but after various attempts to return to the ordinary diet, and especially several deviations from his diet, the sugar no longer completely disappeared. He left this clinic for good on January 9: returning to his old habits, he noticed an aggravation in all the symptoms, thirst, general weakness, manly impotence, weight loss. The maximum urine output in 24 hours during his stay in this clinic was, according to him, six liters. Having come to Naples, he was received at our clinic on January 19, 1874, exhibiting extraordinary weight loss, general weakness, virile impotence. In the somewhat asymmetrical thorax, there was a slight difference in the pitch of the sound on percussion, and in the prolongation of the expiratory sound. On the heart, a little enlarged, a very slight pericardial murmur: the spleen is enlarged, the liver is not accessible to touch. No other symptoms, no pain in the chest or the rest of the body, no cough, no feeling of worry; but hunger, thirst, and a lot of sugar in the urine. On January 20, he emitted 3 liters, 460 of urine which contained 100 g. of sugar per liter, i.e. 340 gr. per day; the next day he made 5 liters, 760 with 570 gr. of sugar in 24 hours. On January 23, he was put into treatment. From the first day, the urine was 1440 cc in quantity, with 60 gr. of sugar per liter, or 86 gr., 4 per day. The following days the quantity of urine remained normal, on average from 1 to 2 liters, with a high specific weight, between 1030 and 1034, while the quantity of sugar oscillated between 30 and 35 per thousand, between 40 and 70 gr. per 24 hours. On February 4, the first absolute fast of 24 hours was ordered, during which the sugar disappeared entirely: but it reappeared at a dose of 30 gr. per liter, as soon as the patient ate, even meat only. So they reduced her ration, and gave her a soft drink made with bicarbonate of soda of lactic acid, and 1/2 gr. Of potassium carbonate, in water: after this treatment with a reduction of half in the quantity of meat), the sugar fell on February 12 and 13 to the proportion from 1 to 2 gr. per liter. Some thoughtlessness committed from time to time brought it back to 20 per 1000. As the ration increased, the sugar returned to 30 gr. per liter, but a new fast on February 23 made it disappear again completely: the return to the ordinary ration of meat again made traces of sugar reappear, which increased day by day up to 5, 10 and 15 gr .; note that the highest figure was reached only when the patient smoked in secret; when he did not smoke, the sugar decreased, and stood between 4 and 5 gr. per 1000. These small quantities disappeared definitively on March 19, after the administration of pure potassium carbonate dissolved in water, for four days, at a dose of 4 gr. in 24 hours. Since then, the sugar remained absent, the quantity of urine was normal, and their specific weight oscillated between 1026 and 1014. Note that this patient, on entering the Clinic, weighed naked (with his shirt and underpants, and he was is always weighed with the same clothes):
January 19, 1874 ....... kil. 49,500 he first continued to lose weight and weighed, - January 21. the 24th the 29th February 2 ... the 4 kil. 48,900 48,600 48,300 48,000 47,500 ”after which it began to resume on February 7th. the 11 the 12 the 13 kil. 48,200 48,600 48,800 49,200 to decrease and descend on February 15 to ........ kil. 48,500 and return on February 20 to ..... . kil. 48,700 and go back down following diarrhea on February 22 to .... kil. 47,200 The weight rose quickly, so much so that it reached on February 23 ... 27 kilos. 47,800 48,800 and remained such for some time, with insignificant oscillations, after a purgation, it descended on March 8 to ...... kil. 47,500 oscillations which are largely understood by the fact that the intestine is more or less full. After the complete disappearance of sugar, the weight of the body gradually increased: we found >>> >> >> on March 19th. April 24 28 April 11. the 13th the 17th the 19th the 27th May 1st. the 5 the 6 the 22 kil. 48,200 48,700 49,300 49,600 49,800 50,100 50,700 51,000 51,700 51,900 52,700 53,100 >>) »» So that since February 22, the day of minimum weight, he had gained in three months of treatment, 5 kil. 900 gr. The temperature always oscillated between 36 and 37 ° C., the pulsations which initially were between 50 and 60, were maintained later between 64 and 72, sometimes going up to 80: the breaths were always between 20 and 24 Minute.
On May 20, this patient, who as a student had, since April, obtained permission to go out every day, suddenly presented sugar in the urine, 8 gr. per liter and per day. Although the patient affirmed that he had not eaten outside of the clinic, I learned that for several days he had been taking rum, which in Naples always contains a lot of sugar: we are willing to believe that he hadn't eaten anything else. In addition, he was struck with a stone in the chest in the street, and so violent that he was thrown to the ground unconscious, felt pains in the right subclavicular region, a region which had been directly struck: he also had a little fever with sonorous groans with small bubbles.
On May 21, the sugar had reached 10 gr. per liter, from the 22nd it dropped to 4g., on the 23rd and 24th it was maintained at 3g. to disappear on the 25th and remain absent until the 30th, the day when the patient escaped our supervision For more than 15 days this patient, according to his own confession, made when I presented him to my audience to take leave, was eating fresh beans (!), cherries, other fruits, and drank wine. Despite this the glycosuria had ceased. She had not yet reappeared at the end of July, the patient assured me in a letter, although for 12 days he had eaten not only green vegetables, but also milk, cheese and fruits (among which the sweeter ones, like pears, plums, etc.) and half-flour, beans , fresh peas, and eat them up to two kilograms per day (!). The circumscribed pneumonia had somewhat reduced the patient's weight: from 53kil, 1, maximum weight on May 22, it had gradually dropped to 51kil, 4, on May 28, to rise to 53kil, 2, on June 23.
In a patient as advanced as this one, I would not have allowed the return to the mixed diet, or even to the Bouchardat menu, before at least six months of rigorous treatment, after the disappearance of the sugar. - If I report this observation among the cases of cure and the last, I must make this reservation that I am in doubt about it: the cure is not final: it is too short a time since he returned to the use of milk and fruit, etc., and then he abuses them again. In any case, this patient has demonstrated that even very advanced diabetes can be cured when the cure is carried out with all its rigor (1). (1) As I correct the proofs, I receive a final note about this patient. In the second half of August, after further abuse of fruit and wine, this patient again noticed sugar in his urine, and by an approximate calculation evaluated it at 5 or 10 grams per liter. He suspended the use of fruit for a single day, and the sugar disappeared.
At the beginning of October, I received a letter from the father who told me: "For a month the sugar had reappeared following a new abuse of fruit and even bread: we knew afterwards that he had also abused liquors and pills containing vomit nut: he took eight in a single day, whereas he should only take two or three. This gave him a sharp intestinal inflammation, from which he died on September 28 ”. So he died of intestinal inflammation! (Author's note.)
January 25, 1874
Diabetes Mellitus and its dietetic treatment
Cantani says that he has "73 cases published above, 52 other cases cured by others than by me, which would make 125 successes obtained in 4 years" and he asked Dr Primavera for his data and ideas on the use of the all meat diet to cure diabetes.
I do not wish to speak here of the patients whom I am treating at present, although in all these cases there are a great number in the process of perfect recovery, and several patients have already returned for some time to the use of carbohydrates: but enough time has not yet elapsed, and I cannot regard them as fully healed. In addition, there are many cases of diabetes cured by my method, by other doctors: so that today we can count diabetes among the most curable diseases. To pretend that a man cured of diabetes could not get it back, even under the conditions in which he contracted it the first time, would be nonsense: just like to claim that one can no longer contract pneumonia, acute catarrh or rheumatism, when you are cured of a first attack, or several. Just as it would be unwise to claim that it is the same disease which recurs after several years, it would be incorrect to maintain that a man, cured of diabetes for one, two or three years and eating everything, experiences a "Relapse" if they contract the disease again after further abuse of mealy or sweets, and under the influence of debilitating conditions. Should it therefore be that the treatment procured future immunity, and that the patient had acquired impunity with regard to the abuse of starchy foods and fruits? It would really be asking too much of a treatment to require such immunity before declaring it effective. Quinine and mercury are not required as much as they are said to be specific, and which do not always even prevent recurrence of morbid manifestations. I cannot cite here the names of all those of my colleagues from Italy or abroad who have obtained success with my treatment: but it would be necessary to add to the 73 cases published above, 52 other cases cured by others than by me, which would make 125 successes obtained in 4 years (1), a figure not to be despised in (1) I asked Professor Primavera for notes on the cases of diabetes treated by him alone . He replied to me by the following letter, which I publish without comment:
Naples, January 25, 1874.
Very honored Professor Cantani,
You ask me for notes on diabetics which you have not seen, but which I have analyzed urine and disease monitoring. Strictly, I don't and which do a disease previously regarded as incurable. Moreover, this cure has become popular in our southern provinces, where everyone orders it, even pharmacists, priests and former patients. Success is assured provided that the treatment is not started too late, provided that it is followed with all the necessary rigor and for a sufficient time. The high frequency of diabetes in these countries means that its beginnings do not escape attention as easily as it once did, and still happens in countries where diabetes is rarer, and therefore is often recognized too late, if the patient does not watch himself, or if he comes across a doctor who does not pay attention then say the exact number, but I can assure that they are roughly twenty in number: some from outside were treated according to your method by foreign doctors, others treated in the same way by Neapolitan doctors, some finally absolutely wanted to be treated by me, always according to your method, henceforth known to all.
The first piece of information I must give you is this: I have never seen a single one of these patients not being cured, and if four of them seemed to resist the treatment, it is because they were not following it, not with enough rigor; but warned by me, they did it, and also came to a complete recovery. This fact is certainly very consoling, I do not explain it by the practice of other doctors who have also administered to their patient several therapeutic agents unrelated to your medication, such as a decoction of quina, strychnine, opium and the like; but, on reflection, let me explain it to myself because the diabetics of the civilian clientele, that is to say rich or at least well-off, do not allow their disease to age: on the contrary, the poor diabetics who resort to hospitals when they really cannot take it any longer, must necessarily provide a contingent of incomplete healings. My second piece of information, which I guarantee to be correct, relates to this fact: patients who do not strictly follow the meat diet often emit in their urine, along with a little sugar, lime oxalate; so that the presence of this salt is very useful for me to deny those who claim to adhere strictly to your treatment, and transgress it more or less, by eating a little bread or fruit (often out of ignorance).
As for the return of diabetes, I have observed several cases of it after eight months and more, up to two years; but I have always seen the sick recovering again with the same treatment. So much so that it can be said, with great probability, if not complete certainty, that any diabetic, once cured by your method, could secure lifelong cure, if he had the patience to repeat the rigorous treatment for two months every semester, and this for a number of years. If I were diabetic this is how I would act, with the firm conviction that I would never die from it. Finally I noted in all these patients, as a constant cause, the usual abuse of flour (bread, pasta in general): only once was this abuse lacking, but there was, on the other hand, abuse of cane sugar (sweets, sorbets, jellies, sweet coffee, etc.).
G. PRIMAVERA.
March 7, 1874
Diabetes mellitus and its dietetic treatment
Incredibly, many of Dr Cantani's diabetic patients were doctors themselves - and they too found that the all meat diet, when done rigorously, worked to cure diabetes. "This case also teaches that there is no need for trauma or moral suffering to reproduce diabetes: the abuse of hydrocarbons is enough." Observations 51-60.
OBSERVATION LI. MRG, 47 years old, from Terra di Lavoro, a habitual amylivore, with an adipose constitution, himself noticed polyuria in 1871, and a few months later progress in weight loss and weakness: for that, and for unquenchable thirst, with continual dryness and ar- teness of the mouth, and above all for sexual debilitation, he had recourse to his doctor, the distinguished doctor Leonardo Bian- (1) In Barth, Gazzetta di medicina e di scienze naturali, di Malta, di GAVINO Gulía, Anno II, Nov, 15 and 16. Malta 22 luglio 1873. (2) In Barth, loc. cit. and all the diabetic symptoms were gone; since then he has been doing well. This observation has already been published by Dr. P. Sammut (2). chi. In April 1873 the urine, about 7 liters per day, had the specific weight of 1035, with 130 gr. of sugar per liter, about 900 gr. per day. After a cure almost exclusively meat, with tolerance of a few berberages, a little butter, a little red wine, which was prescribed to him by Doctor Bianchi, the patient improved extraordinarily quickly, so that ' after eight days, he emitted only 2 liters of urine, with 70 g. of sugar per liter, 140 gr. about sugar per day; after five more days, he emitted only a liter and a half of urine, with 49 g. of sugar per liter. Consulted on May 4, I insisted that the cure became rigorous, I prohibited butter, vegetables and wine, granted by the transaction of Doctor Bianchi: after fifteen days, the sugar completely disappeared from the urine, the volume of which fell to 700 cc, the patient regained his strength and has been doing well until this day (September 1874), where I have received news from him: for more than a year, he returned to mixed feeding.
OBSERVATION LII. - M. Guiseppe Durini, 47 years old, from Bolognana (Chieti) (1) very fat in 1866, usually eating large quantities of flour, fruits and sweets, began little by little, without any known cause, and especially without having experienced any moral emotion, to lose weight; in the last seven months he became extraordinarily emaciated: at first, this symptom was attributed to diarrhea which had occurred in the meantime. Finally he showed himself to Doctor Colombo de Nicola, who noticed polyphagia, polyuria, polydipsia, vision impairment and impotence, suspected diabetes and confirmed this suspicion by urine analysis. On January 2, 1874, the patient emitted 5 liters of urine in twenty-four hours, with 65 gr. of sugar per liter, which makes 325 gr. of sugar per day; after eight days of rigorous treatment, Primavera observed the complete disappearance of sugar. The patient continued to be perfectly well; he returned to see me on April 7, 1874, comforted, flourishing in appearance, perfectly healthy, ruddy in color, with greatly improved eyesight. I allowed her the pastures, the wine, the coffee (without sugar), some unsweetened fruits. I saw him again in the best state of health on May 17, 1874: his urine was completely free of sugar, weighed 1022, because it was rich in urea by the fact of (1) He himself wanted to be named here, meat diet; I then allowed him the starchy foods: at the last I heard he was still doing very well, and feeling stronger than ever.
OBSERVATION LIII. - Doctor G., a very distinguished doctor and director of a hospital in one of the most important towns of Campania, about 50 years old, of fat constitution, lover of starches, contracted diabetes mellitus in 1871, presenting the usual symptoms, with weight loss and considerable weakness. Having learned of the happy results that I had since obtained at my Clinic, which a young student of his parents attended, he submitted to my treatment, and followed it with great rigor. He recovered completely, and used a mixed diet for a long time: today he has gained weight again, he is flourishing in health, and a few weeks ago (August 1874), I saw him in consultation for one of his patients (1).
OBSERVATION LIV. Doctor Pasquale M., distinguished doctor from Salerno, about 60 years old, of normal constitution, extremely amylivorous, suffering from diabetes for two years, with all the ordinary symptoms; so emaciated and weakened that it was difficult for him to continue his visits, and a little frightened also by the sight of the progress of the diabetes in the dean and the most renowned of the doctors of Salerno, Doctor Centola (who never did the treatment of rigorous meat diet, wasting his time taking arsenic, strychnine, and following the Bouchardat diet), Doctor PM submitted to my treatment, followed it rigorously, and recovered completely; therefore, fully recovered in possession of his strength and with normal urine, although he had returned to mixed food for about a year, I saw him again a few months ago (in March 1874 ), in a consultation in Salerno, which he attended as an attending physician.
OBSERVATION LV. - Dr. Guiseppe B., from Randazzo, who usually ate a lot of starchy foods, ill, according to what he wrote to me, for three and a half years, is now fully recovered: his urine are normal in specific weight, free from sugar, although, for several months, (1) Special considerations, and the wishes of this distinguished colleague himself, require me to suppress the other details: it is the same for the following cases. he returned to a mixed diet about a year ago. I saw him again a few months ago (in March 1874), in a consultation in Salerno, which he attended as an attending physician, he returned to mixed feeding. On February 26, 1874, this distinguished colleague wrote to me that having interrupted the rigorous treatment too early, he relapsed four times, so much so that he began to regard my treatment as a palliative which suppressed, but did not cure diabetes; but after having followed it for a sufficient time, he was able to return to a mixed diet without seeing the sugar reappear in the urine: he then reconsidered his previous opinion.
OBSERVATION LVI. MF Saverio M., from Borgia (Cantanzaro), 53 years old. At the age of 40 he experienced, as a result of serious sorrows, sufferings in his stomach and intestines, with diarrhea: but he recovered completely, got married at 14, had children and did well until the age of 49. At this age, and with no known cause (apart from the daily abuse of mealy seeds), he began to present the first symptoms of diabetes, which he recognized in him a year later by Doctor Cirillo, who prescribed him a treatment which was followed for two and a half months , and which consisted of a diet composed mainly of meat, eggs and milk, with limitation for the use of flour, all accompanied by a prescription of cinchona, strychnine, rhubarb and baking soda. A great improvement followed, but hardly the cure ceased, the patient relapsed and more seriously than the first time. So Doctor Cirillo prescribed a more rigorous treatment, ours, forbidding the use of fruits, milk, vegetables and flour, and adding lactic acid to the previous drugs. The patient got better again, but as he was not sufficiently rigorous in his diet, he presented on January 27, 1874, when I was consulted, 30 gr. of sugar per liter, with a polyuria of 2 to 3 liters per day, and the specific weight of 1023. Subject to my rigorous treatment, the urine, examined on February 15 by Professor Primavera, had the specific weight of 1015 and was completely free of sugar; they were still similar on April 27, 1874. The patient continues to be well, although he has resumed the moderate use of flour.
OBSERVATION LVII. - Mr. Giacamo F., 33 years old, from Tunis (Africa), client of Doctor Quintilio Mugnaini. He had two brothers who died of diabetes, the second from phthisis after consulting the best doctors in the largest cities in Italy, the rigor of my cure. The patient himself, as his brothers had done, ate almost exclusively on flour and very fond of sweets; he never had moral emotions. In September 1873, he noticed that he had a slight polyuria, that he got up three times at night to urinate, while before that he always slept through the night. The example of his brothers made him seek advice from his doctor, Doctor Quintilio Mugnaini, who analyzed the urine with the help of the pharmacist Sinigaglia, and finding them sweet, diagnosed diabetes, and submitted the patient to my cure. After three days, the urine was free of sugar; after ten days, he ate a little bread, and the urine picked up a little sugar, but with a much less clear reaction than the first time: this sugar disappeared again after a more careful treatment of two months. After forty-five days the patient returned to a varied diet, for he was feeling quite well, and his nutrition was good. On February 25, 1874, he came to Naples, and wanted to consult me: his urine, examined by Professor Primavera, was free of sugar. This case is very interesting because it demonstrates, not only that diabetes is often a family disease, thus affirming its constitutional character, but also, by the sad antecedents of the two brothers, neither long enough nor rigorously enough. treated, that the third brother followed the same route and succumbed, if he had not been saved by coming in time to be treated and to follow the treatment exactly. He also demonstrates that there are not two kinds of diabetes, one curable, the other incurable: curability depends on the degree reached by the disease, on the period at which the disease is recognized, and the patient subjected to rigorous treatment.
OBSERVATION LVIII. Mr. Carlo de S., 44 years old, military employee on the island of San Stefano. As a result of a great abuse of starchy substances, for he seldom ate meat, and without any other known cause, he suffered from diabetes; for some time he kept his illness concealed, although he suffered from polyuria, with thirst, impotence, great emaciation and extreme weakness. In June 1873, the presence of sugar was found in the urine, and he followed a treatment, but not with sufficient rigor: he ate almost exclusively meat, bis. The sugar gradually disappeared from the urine, and the treatment continued for five months. The urine remained free of sugar, and the patient recovered, assumed a flourishing appearance, and felt robust and strong. Having returned then to abuse flour and to abandon the meat almost completely, after a month we found sugar in the urine, but in small quantities. Professor Primavera, on March 1, 1874, found only 5 gr. of sugar per liter in urine emitted on an empty stomach at 11 am; the urine presented this interesting thing, that it was rare in the morning, but very abundant after the meal, during which he consumed so much flour. The urine, after the meal, contained up to 50 gr. of sugar per thousand. It is a kind of intermittent diabetes depend on the diet, such as starting diabetes. On March 23 began my rigorous cure, and shortly after the urine was completely free of sugar. In June 1874 he was still doing perfectly well, although he returned to a mixed diet after only a month of rigorous treatment.
OBSERVATION LIX. Mr. Nicolangelo S., 53 years old, from Forino (Avellino). Diabetic since August 1873, by abuse of flour and without other known cause, he also presented a symptom of beginning diabetes, that of the intermittence of diabetic phenomena (polyuria, thirst and sugar in the urine, only after meals, usually rich in starch; in the morning urine is normal and completely free of sugar). - Come to Naples to consult me, he presented me, on January 3, 1874, urine emitted after meals, and whose specific weight was 1034, with 60 gr. of sugar per liter: he immediately submitted to my rigorous cure; from January 22 the urine was sugar free, and weighed 1018: the same on February 23. The severe cure was only continued for a short time: nevertheless, according to the news received, he is still doing perfectly today, although he makes moderate use of the mixed diet.
OBSERVATION LX. Mr. Aniello S., lawyer, 47 years old, from Carbonara de Nola. Recognized diabetic by Doctor Mele in Ayril 1872; after 2 days of rigorous treatment, his urine no longer contained sugar; he continued thus for a month only, and then was very well, although he ate everything; however relying too much on his regained health, then he abused for a long time flour, sweets and wine, so that again contained sugar; however, the patient was subjectively well. He resumed the cure in January 1873, for 40 days; his urine got rid of the sugar, and he was well, although he ate everything. But in the carnival of 1874, returning to the abuse of sweets, he began to urinate more, and felt his virile power go away: the urine examined contained sugar: here is therefore a relapse after 13 months of well- be and mixed diet, brought about by the abuse of sugary foods. On March 7, 1874, the urine examined by Professor Primavera showed the weight of 1035 with 70 gr. of sugar per liter: but there was no polyuria yet. The cure resumed, the sugar soon disappeared, and the patient regained virile power. - He continues to do well, to what Dr Mele assured me in September 1874. - What is remarkable in this case is that it shows that an individual, who has once contracted diabetes, should not never again abuse the sweets, which are even more perilous and harmful than the mealy ones themselves. This case also teaches that there is no need for trauma or moral suffering to reproduce diabetes: the abuse of hydrocarbons is enough.