Trincavella (1476–1568), a Venetian, observed three cases of dia betes. In one, the etiology was attributed to persecution and grief. In another, the relatives are said to have demonstrated the truth of the Galenic doctrine that diabetic urine is the unchanged drink, by fre quently tasting the urine and finding the taste identical with what the patient had been drinking. Cantani suggests that the drink in this CaSe Was SWeet tea.