Griesinger in 1859 published an analysis of 225 cases of diabetes; and though only eight were his own and the others all from the litera ture, his contribution was valuable for clinical experiments and sound judgment. He compiled the first evidence indicating excess in sugars and starches as a cause of diabetes, but concluded that it could not be the most important cause, or many more persons and some entire races would have diabetes. He overthrew various current errors, but somehow convinced himself in painstaking experiments that diabetics may excrete large quantities of sugar in the sweat, as reported by several other authors. From the negative findings in necropsies, he regarded diabetes as generally a functional disorder. His most notable achievement was the demonstration, in three separate experiments on a single patient, of sugar excretion equalling exactly 60 percent of the protein of the diet.“ These facts, remaining constant under varied conditions, cannot be accidental; they seem much more to contain the law of the relation in which, in this individual on exclusive meat diet, the production and excretion of sugar stands to the quantities of ingested meat."