OBSERVATION LXI. - M. Guiseppe d'A., Priest, 56 years old, from Acireale. According to the report of his attending physician, the distinguished doctor Gaetano Vigo, this patient has long abused flour and sweet dishes, and ate a lot while burning little, thanks to his way of life. After the death of his mother, which happened on February 14, 1871, and which grieved him a lot, he began to experience a great dryness of the mouth, with thirst, polyuria, and general prostration of strength: he also noticed that a few drops of urine which had fallen on black cloth, left a viscous white stain there. The chemical examination of the urine was not made until 1872, when the patient consulted Doctor Vigo, who found him notably emaciated, weakened to the point of not being able to take a short walk, and who observed in the urine, the specific weight of 1038, about 120 gr. of sugar per liter. The patient then followed the rigorous treatment prescribed by Doctor Vigo, and the urine became free of sugar; but he did not want to continue it beyond 25 days, and still indulging in the abuse of flour and candy, he soon relapsed into melituria, and more seriously than before. The urine reached the specific weight of 1042. The patient resumed cure, and, encouraged by Doctor Vigo, who understood the culmination of my therapeutic conception in this disease, he followed it this time in all its rigor, during four whole months, during which the weight of his body increased by 4 kilogr. Since August 10, 1872, sugar has not reappeared in the urine, the specific weight of which hovered around 1033, and the patient enjoyed the best health, although he had returned, this time with more moderation, to the use of strawberries. I really enjoyed receiving a letter from Dr Vigo, which expressly confirms my opinion as to the frequency of diabetes in these regions, a frequency which is directly related to poverty, especially since “ starchy or sweet food is almost exclusive, even for the upper class. And very cleverly, Doctor Vigo adds that idleness can greatly contribute to the development of diabetes; I believe that this is very probable, on account of the slowing down which idleness brings about in material renewal, in combustion in general, and, in amylivores, in the combustion of hydrocarbons, or of sugar. 

OBSERVATION LXII. MB, from Trani, client of the brave doctor Nanula, who noted the existence of diabetes in him, with 25 to 30 gr. of sugar per liter: the patient ate mainly starchy foods, and suffered from a notable general weakness, with polyuria and ardent thirst. After fifteen days of treatment, the urine still contained 15 gr. of sugar per liter, but they had decreased in quantity, and the state of strength was better: after a month, the sugar had completely disappeared: the patient remained healthy, regained his strength and was overweight: according to the latest information, he continues to enjoy the best health, although he has returned to diet mixed. 

OBSERVATION LXIII. - MG lawyer, from Trani, 60 years old, amylivore par excellence, was introduced to me as diabetic by Doctor Nanula, about three years ago; great prostration, impotence, thirst and especially troublesome polyuria. The urine contained 30 to 35 gr. of sugar per liter. Subjected to my cure, which he followed rigorously for two months, the urine became free of sugar; he rapidly improved in strength and nutrition, and resumed his pleadings in court with all the ardor of his best years. The urine examined again by the the patient remained healthy, regained his strength and was overweight: according to the latest information he continues to enjoy the best health, although he has returned to mixed food. Doctor Nanula these days are sugar free, although for several months he has been eating everything. 

OBSERVATION LXIV. M. Domenico Castronuovo, doctor from Carbone (Basilicata), 52 years old, almost exclusive amylivore, ill since October 1873, with unusual and increasing weakness of the lower limbs, virile impotence, aridity of the mouth, was recognized as diabelic by the doctor. Maturi, and on his advice began the treatment, rigorous meat diet (accompanied by hydrotherapy). On December 17th, the quantity of urine was reduced almost to normal, and Doctor Maturi observed by repeated analyzes the gradual decrease in sugar. The rigorous treatment was continued until January 30, 1874; after this day, the patient feeling cured returned to the mixed diet, and returned to it a little too abruptly, for he immediately allowed himself the use of bread, pastries, even sweetened coffee - and this above all because of the not very flourishing conditions in which he found himself, and which did not not allowed to maintain any longer the absolutely meaty diet. Nevertheless he was doing well, his strength was increasing: he was completely recovered. Towards the first days of February, he presented to the clinic, where he was received as a further observation of the disease. It was doing very well with the ordinary mixed regime, its temperature oscillating around 36°, 5 C .; with 64 to 68 beats, and 12 to 16 breaths per minute, the urine was kept completely free of sugar, its specific weight varied between 1022 and 1025, and its quantity sometimes exceeded, sometimes was not reaching one liter per 24 hours. On March 5, the patient left the clinic in the best condition. - This patient is cured rather quickly because he began and followed the rigorous cure soon after the onset of diabetes, while this one was still in the period of beginning diabetes. 

OBSERVATION LXV. Luigi B., 31 years old, merchant from Soriano (province of Rome). Suffering from great thirst and polyuria, with hunger and growing general weakness, weakness also of the reproductive organs, he was received at my clinic on March 5, 1874. He never ate only a little meat, but ate mainly flour. , especially abusing sweet pasta; he had neither moral emotions nor wounds: for ten years he had suffered a burning sensation in the epigastrium, which disappeared when several glasses of rum, some belching: these sufferings disappeared with the onset of diabetes. He suffered mental distress, but it was long after the existence of diabetes was discovered. He lost his father to phthisis. - At the clinic, he presented more than two and a half liters of urine within 24 hours; their specific gravity was 1042; they contained 277 grams of sugar per day. On March 10, he was put in treatment, he was given only meat, with lactic acid in water, and alcohol mixed with water, instead of wine: on March 11, he only eliminated 1400 cent. cub. urine, with a specific weight of 1021 and 15 grams of sugar per liter, about 22 grams per day. On March 12, Fehling's solution already indicated the disappearance of the sugar; the quantity of urine was 1970 CC, their specific weight 1015. - The urine remained free of sugar, their quantity oscillating between 1200 and 1700 CC, and their specific weight between 1018 and 1023. The temperature of this patient was maintained throughout his stay in the clinic between 36 °, 2 and 360.5 C .; only once did it rise to 370.9 C. due to a temporary febrile attack: the pulse oscillated between 54 and 74, rarely reaching 70 or 72; breaths were almost always a little frequent, between 20 and 24, without any lung disease. - The patient left the clinic on April 3, in the best state of health and strength: for some time he had returned to a moderate mixed diet.

OBSERVATION LXVI. - Mr. Francesco S., 60 years old, owner in Castellana di Bari, diabetic for a year, following abuse of flour and fruit, stubborn smoker, and gouty, was subjected to the rigorous cure by Doctor Nicola dell'Erba in November 1872. He was then 50 gr. of sugar per liter, with a polyuria of 5 to 6 liters per day; ten days after the start of treatment the urine was normal in quantity and quality, and all diabetic symptoms had disappeared. After a very rigorous cure, prolonged for two months and regularly followed, and a rationally graduated return to mixed food, he was able to return to the use of flour, although in moderation: even today he enjoys better health. 

OBSERVATION LXVII. - Mr. Carmine di F., from Alatri (prov. Of Rome), 54 years old, diabetic by abuse of flour since January 1872, resorted to the treatment of Dr. Raffaele Giorgi, when he suffered from an unquenchable thirst with discolored urine, of sugar (not dosed). Doctor Giorgi, after recognizing the diabetes, submitted the patient to my treatment, absolute meat diet and lactic acid; Only six days later, he examined the urine, he found only a few traces of sugar there: however the patient already felt improved: he was stronger, and no longer experienced the symptoms peculiar to diabetes. After 34 days of very rigorous treatment, the patient no longer being able to submit to such great penance, Doctor Giorgi allowed him to use bread in moderation; the urine remained free of sugar. Seeing him two months later, this patient presented normal urine, and was doing well anyway. From what the doctor wrote to me. Giorgi, in June 1874, the patient continued to do well; her urine remained normal. 

OBSERVATION LXVIII. - MN N., owner in Chieti, 40 years old, major consumer of hydrocarbons. In 1872 he suffered from eczema; in May 1873, he began to experience an extraordinary general prostration, especially a weakness of the lower limbs, with simultaneous emaciation, intense thirst, inextinguishable, and emission of very abundant urine: the morale was also affected, the patient became uneasy. , irascible, which he was not previously. In the first days of July 1873, talking with two distinguished doctors, he made them suspect that it was a question of diabetes mellitus: the urine was examined, and it was found that their specific weight was 1033, that they contained 40 gr. of sugar per liter, and that it was emitted 3 liters per day. Condemned to the meat diet, the sugar completely disappeared in three days, the specific weight of the urine fell to 1020, and from the first day of the treatment their quantity had fallen back to normal. Only the general weakness increased with the meat diet, a fact which is observed in several cases (but not in all) at the beginning of this radical modification in the diet, to give way later to a progressive increase in strengths. The cure was interrupted for ten days, and we saw the quantity of urine increase a second time, the sugar reappearing there, and their specific weight go up to 1030. After that the most rigorous treatment was resumed, and continued for six months: the last three months it is softened with a little grass. The sugar quickly disappeared from the urine again, and after six months of abstinence from all starchy or sweet foods, months without any trace of sugar reappearing in the urine, which, on the contrary, showed itself to be richer than before in uric acid and urates, since the patient had eaten everything. The latest news on this patient was communicated to me by Doctor Paolucci, my clinical coadjutor (I had them in September when I was correcting these tests); they confirm his complete good health, and the absolute absence of sugar in his urine. 

OBSERVATION LXIX. - Monsignor B., bishop of C., 49 years old, ate mainly hydrocarbons, and, without any other known cause, had been ill for some time, suffering from thirst with polyuria, general debilitation and mediocre weight loss, because he was fat before he got sick. His urine showed, in Primavera on January 27, 1874, a specific weight of 1033, an amount of 6 to 7 liters per day, and contained 100 gr. of sugar: 600 to 700 gr. per 24 hours. He submitted to the rigorous treatment, less according to the advice of the doctors, than by his own conviction, for he had been aware of our treatment, and had been able to realize, thanks to his great intelligence, of the nature of the disease and the curative method. At first, he wanted to experiment on himself the value of our treatment, and tried a little bread, after several days of absolute meat diet: but the constant appearance of sugar after each attempt, because this intelligent bishop had learned wonderfully at making use of chemical reagents, decided him to follow the most rigorous regimen for three consecutive months; from March 1 to May 30, for three full months, he followed him without the slightest interruption, with all the rigor I could demand. In June, he began to eat grass, bran bread, and drink wine, always examining the urine, which remained free of sugar; on June 23, they were again examined by Professor Primavera, who found them the specific gravity of 1008 (there was still a polyuria of 3 to 4 liters in 24 hours), but complete absence of sugar. 

OBSERVATION LXX. Canon Giovannandrea G., from Ischitella del Gargano, 67 years old, suffering from mild diabetes as a result of eating too much starch, and which seems to have started in September 1873 or some time before: examined by the professor Fede, who noted the presence of 50 gr. of sugar per liter of urine, he was treated with 5 ayril; from with all the rigor that I could demand. In June, he began to eat grass, bran bread, and drink wine, always examining the urine, which remained free of sugar; on June 23, they were again examined by Professor Primavera, who found them the specific gravity of 1008 (there was still a polyuria of 3 to 4 liters in 24 hours), but complete absence of sugar the first days of May, at the second analysis, the urine was free of sugar. At the end of June, Professor Fede again observed in this patient (whom I also saw in consultation with Fede) the complete absence of sugar, although he had returned for more than a month to the moderate use of sugar and starchy foods.